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A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC

Join a study on new treatments for advanced lung cancer.

Recruiting
18 years and older
All
Phase 3

This study is for adults with a type of lung cancer called Stage III Unresectable NSCLC. This means the cancer is locally advanced and cannot be removed by surgery. The study will test two medications, Durvalumab and Domvanalimab, given after patients have had a treatment called chemoradiation (using chemicals and radiation to kill cancer cells).

The study will compare how well these medications work when given together or with a placebo (a "fake" treatment). To join, patients should be 18 or older, have a certain type of lung cancer, and not have gotten worse after chemoradiation. They also need to have good health overall. Some people can't join if they have other serious illnesses or have had other types of cancer recently.

  • Duration: Participation involves multiple visits over several months.
  • Compensation: Participants may receive compensation for their time and travel.
  • Risks: Potential side effects from medications and treatments.
Study details
    Non-Small Cell Lung Cancer

NCT05211895

AstraZeneca

12 April 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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