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Atezolizumab in Combination With Stereotactic Body Radiation Therapy (SBRT) and Surgery for Relapsed Osteosarcoma

Atezolizumab with radiation and surgery for relapsed osteosarcoma trial.

Recruiting
50 years and younger
All
Phase 1

This study is testing a treatment for **relapsed osteosarcoma**, a type of bone cancer that has returned and spread to the lungs. It combines a medicine called **Atezolizumab**, a type of immune therapy, with **Stereotactic Body Radiation Therapy (SBRT)**, which is a precise form of radiation, and surgery to remove lung tumors. The goal is to see if this combination is safe and if it helps patients better than other treatments.

  • This study is for people whose cancer has come back only in the lungs and can be treated with surgery.
  • Participants will receive both radiation therapy and surgery, and they need to be available for multiple visits.
  • If eligible, participants must not have severe ongoing health issues and must agree to use birth control during and after the study.

Participants will need to sign a consent form. Women must have a negative pregnancy test, and everyone must agree to use birth control. The study aims to improve survival rates by using this new treatment method. If you're interested, talk to your doctor to see if this study might be a fit for you.

Study details
    Osteosarcoma
    Pulmonary Recurrence of Osteosarcoma

NCT06492954

Emory University

26 April 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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