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Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

Comparing Remibrutinib and Teriflunomide for Relapsing Multiple Sclerosis.

Recruiting
18-55 years
All
Phase 3

This study is looking at how safe and effective two medicines, called **remibrutinib** and **teriflunomide**, are for people with a condition called **relapsing multiple sclerosis (RMS)**. RMS is a type of disease where the immune system attacks the brain and spinal cord, causing problems like weakness and vision issues. The first part of the study lasts up to 30 months and involves about 800 people. The second part can last up to 5 years for those who continue with remibrutinib. To join, you must be between 18-55 years old, have a diagnosis of RMS, and meet specific health criteria.

  • Study duration can be up to 5 years.
  • Participants will receive medication and regular health check-ups.
  • Risks include potential drug side effects, requiring regular monitoring.

Note: You cannot join if you have other serious health conditions, are pregnant, or have a history of substance abuse. Always consult with your doctor to see if this study is right for you.

Study details
    Relapsing Multiple Sclerosis

NCT05147220

Novartis Pharmaceuticals

30 March 2025

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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