The **RECOVER-ENERGIZE** study is designed to find treatments for exercise intolerance and post-exertional malaise (PEM), symptoms that occur after having COVID-19, also known as **PASC** (Post-Acute Sequelae of SARS-CoV-2 Infection). The study is flexible and can be changed as new information is discovered. Participants are divided into groups to try different treatments or be in a control group with no treatment. The goal is to improve patients' ability to exercise, do daily activities, and overall quality of life.
To join the study, you need to be at least 18 years old, have had COVID-19, and still experience symptoms like tiredness or shortness of breath for at least 12 weeks. You can't join if you have an active COVID-19 infection, have a history of Chronic Fatigue Syndrome unrelated to COVID-19, or are part of another clinical trial.
**Key points:**
- The study tests treatments over various healthcare settings.
- Participants are randomized to groups, possibly receiving a treatment or not.
- Steps are taken to ensure safety and adapt the study as new data emerges.
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