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Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen

Testing Tozorakimab for lung infection in hospitalized patients needing oxygen.

Recruiting
18 years and older
All
Phase 3

This study is testing a new medicine called tozorakimab to help people with serious viral lung infections who need extra oxygen to breathe. We want to see if this medicine can prevent death or the need for machines like IMV (Invasive Mechanical Ventilation) or ECMO (Extracorporeal Membrane Oxygenation) that help with breathing. You can join if you are 18 or older, hospitalized with a viral lung infection, and need oxygen because your blood oxygen level (SpO2) is low. SpO2 is a measure of how much oxygen is in your blood. You can’t join if you have other types of lung infections or conditions causing low oxygen that are not due to a virus.

  • The study involves taking tozorakimab along with your usual care.
  • Participants need to be in the hospital and require extra oxygen.
  • Exclusion if using breathing machines (IMV/ECMO) at the start.
Study details
    Viral Lung Infection and Acute Respiratory Failure

NCT05624450

AstraZeneca

26 April 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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