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Study of CC-96191 in Participants With Relapsed or Refractory Acute Myeloid Leukemia

Exploring CC-96191 for hard-to-treat acute myeloid leukemia.

Recruiting
18 years and older
All
Phase 1

This study is for people with Relapsed or Refractory Acute Myeloid Leukemia (R/R AML). Acute Myeloid Leukemia is a type of blood cancer that comes back or doesn't respond to treatment. The study will test a new drug called CC-96191 to see if it's safe and if it helps people with this kind of cancer. The study has two parts: Part A will test different doses of the drug to find the right amount, and Part B will test the best dose to see how well it works.

  • The study is for adults (18+) who have tried other treatments that didn’t work.
  • Participants must not have certain health problems like other cancers or heart issues.
  • Participants will need to agree not to use certain medications during the study.

If you join, you will be monitored closely for any side effects. Participants should not be pregnant or breastfeeding and must use birth control if needed. This study is not for people with certain types of leukemia or other serious health conditions. If you have more questions about joining, talk to your doctor.

Study details
    Leukemia
    Myeloid

NCT04789655

Celgene

1 March 2025

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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