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Sympathetic Overactivity in Post-traumatic Stress Disorder

Exploring new treatments for PTSD-related stress responses.

Recruiting
18-65 years
All
Phase N/A
  • Simplified description (AI rewritten)
  • Technical description (Original)

Post-traumatic stress disorder (PTSD) is a mental health condition that often happens after experiencing a very scary event. People with PTSD have a higher chance of having heart problems and high blood pressure. This study looks at two therapies to help manage these risks: Device-Guided Breathing (DGB) and Transcutaneous Vagus Nerve Stimulation (tVNS). DGB uses a special machine to help people breathe slowly, which can lower stress and blood pressure. tVNS uses a gadget that sends gentle signals to a nerve in the neck, which can help calm the nervous system.

The study will last for 8 weeks, and participants will use one of these methods for 15 minutes each day. The goal is to see if these methods help improve heart and blood pressure health in people with PTSD.

  • Study Duration: 8 weeks of daily therapy.
  • Participants: Veterans with or without PTSD, without major heart issues.
  • Exclusions: Drug or alcohol misuse and certain medications.
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Study details
    Post-traumatic Stress Disorder
    Prehypertension

NCT01627301

Emory University

30 March 2025

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