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Efficacy and Safety of Lonigutamab in Subjects with Thyroid Eye Disease (TED)

Testing Lonigutamab for Thyroid Eye Disease (TED) safety and effectiveness.

Recruiting
18-75 years
All
Phase 1/2

This study checks how safe and effective a medicine called lonigutamab is for people with Thyroid Eye Disease (TED). TED is a condition where the eyes can bulge or feel irritated because of thyroid problems. The study is in Phase 1/2, which means it's early in testing but involves multiple centers and doses.

  • The study is for adults aged 18-75 with specific eye symptoms.
  • Participants must not have certain health issues like hearing problems or diabetes.
  • Participants should not have used certain medicines or treatments for TED recently.

It's important to know that you have to agree to use strong birth control if you join. If you've had certain treatments or surgeries for TED before, you might not be able to join. The study involves several visits to the clinic and might include some risks, like any clinical trial. Always talk with your doctor to understand if this study is a good fit for you.

Study details
    Thyroid Eye Disease

NCT05683496

ACELYRIN Inc.

7 December 2024

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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