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Pentoxifylline in Diabetic Kidney Disease

Exploring pentoxifylline effects on diabetic kidney disease.

Recruiting
18 years and older
All
Phase 4
  • Simplified description (AI rewritten)
  • Technical description (Original)

Pentoxifylline (PTX) is a medicine used since 1984 for leg blood vessel problems. Now, it's being studied to see if it helps protect kidneys in people with diabetic kidney disease (DKD), a condition where kidneys are damaged due to diabetes. In the U.S., DKD is a leading cause of chronic kidney disease and end-stage renal disease (ESRD)

  • The study requires only 2 in-person visits, with other contacts done by phone.
  • Participants must have type-2 diabetes and fit certain kidney function criteria.
  • The study could help reduce the need for costly kidney treatments like dialysis.

To join, you must be a U.S. Veteran receiving care at a participating VA hospital and meet specific health criteria. Some exclusions apply, like type-1 diabetes or recent organ transplants. If successful, PTX could lessen the burden of kidney disease on Veterans.

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Study details
    Diabetic Kidney Disease

NCT03625648

VA Office of Research and Development

17 May 2025

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