This study looks at how safe and effective a medicine called ozanimod is for people with ulcerative colitis (UC). UC is a condition where the large intestine, also known as the colon, gets inflamed, causing stomach pain and diarrhea. People with moderate to severe UC can join this study. The study aims to see if ozanimod can help improve symptoms and the quality of life (QOL) of people with UC.

Participants need to have had UC symptoms for at least 3 months and should have a certain level of disease activity, which is measured with a score called the Mayo score. This score helps doctors see how bad the UC is by looking at different symptoms. Participants should have had a colonoscopy, which is a test where doctors look inside the colon, to check the extent of the disease.

• The study is ongoing; check if enrollment is open.
• No surgery or major procedures during the study.
• Participants will be monitored for safety and changes in symptoms.