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A Study of Disitamab Vedotin in Previously Treated Solid Tumors That Express HER2

Researching Disitamab Vedotin for HER2-positive solid tumors after treatment.

Recruiting
18 years and older
All
Phase 2

This study is for people with advanced or metastatic solid tumors, which means the cancer is large or has spread. The tumors must have a marker called HER2. The study is testing a new drug called disitamab vedotin (DV). DV is an antibody-drug conjugate (ADC), a special medicine that finds and attacks cancer cells. Participants will get DV every two weeks to see if it helps treat their tumors and to check for any side effects, which are unwanted changes in the body.

  • Duration: Participants receive treatment every 2 weeks.
  • Participation Requirements: Includes having a HER2-positive tumor and certain types of cancer such as head and neck, lung, ovarian, or endometrial cancer.
  • Risks: Possible side effects vary and include any reaction the body may have to the drug.

To join, participants must meet specific criteria, such as having previously received certain treatments. Some cannot join if they have received specific prior treatments or have certain health conditions. This study aims to find out if DV can help treat different types of cancer connected to the HER2 marker.

Study details
    Carcinoma
    Squamous Cell of Head and Neck
    Carcinoma
    Non-Small-Cell Lung
    Ovarian Neoplasms
    Endometrial Neoplasms

NCT06003231

Seagen Inc.

13 December 2024

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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