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A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis

Testing Amlitelimab for safety and effectiveness in treating eczema.

Recruiting
12 years and older
All
Phase 3

This clinical study tests a new medicine called amlitelimab to see if it helps people aged 12 and older with moderate-to-severe atopic dermatitis (AD), a skin condition causing red, itchy patches. The study compares amlitelimab to a placebo, which looks like real medicine but doesn’t contain any active ingredients. Participants who don't respond well to creams or other treatments can join. The study lasts up to 44 weeks, with up to 10 clinic visits.

  • The main treatment lasts 24 weeks; there’s a 16-week follow-up for some.
  • Participants can join an extension study lasting 28 weeks with 9 visits.
  • Eligibility includes being 12 years or older and having AD for at least a year.

Before joining, doctors will ensure participants don't have other serious health issues, like infections or a history of cancer, which might affect the study. It’s important to talk to a doctor to decide if participating is right for you.

Study details
    Dermatitis Atopic

NCT06130566

Sanofi

30 March 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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