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Datopotamab Deruxtecan (Dato-DXd) and Pembrolizumab With or Without Platinum Chemotherapy in 1L Non-Small Cell Lung Cancer (TROPION-Lung07)

Study on new lung cancer treatment options with Dato-DXd and Pembrolizumab.

Recruiting
18 years and older
All
Phase 3

This clinical trial is exploring treatments for a type of lung cancer called non-small cell lung cancer (NSCLC) that has spread or is advanced. Patients will be divided into three groups to test the effectiveness of different drug combinations, including a new drug called datopotamab deruxtecan (Dato-DXd), along with pembrolizumab and possibly chemotherapy.

The goal is to see how well these treatments work and how safe they are. The study will look at how long patients live without the cancer getting worse (Progression Free Survival or PFS) and overall survival (OS). Eligible patients must be adults who have not received prior treatment for their advanced cancer and have a specific type of tumor.

  • Duration: The study includes a screening period, treatment phase, and follow-ups.
  • Compensation: Not mentioned in the study details.
  • Risks: Potential side effects from the drugs used in the study.
Study details
    Metastatic Non Small Cell Lung Cancer

NCT05555732

Daiichi Sankyo

26 April 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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