Image

Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 1

Exploring new alcohol treatments for HIV patients: Small study underway.

Recruiting
18-99 years
All
Phase 2

This study explores using **off-label medication** (medication used for purposes not officially approved) to help people with **Alcohol Use Disorder (AUD)**, who also have **HIV**, reduce their alcohol use. Over 12 weeks, participants will receive medication, medical management (MM), and counseling by a **clinical pharmacist**. Counseling will include feedback, advice, and motivation to change alcohol use habits and manage taking many medications (five or more) safely. Participants will be offered a medication called varenicline in the first part of the study. The goal is to see how well this plan works and how patients feel about it. Participants will have interviews, bring their medication bottles to visits, and complete tests about their readiness to change and alcohol use. They will also be screened for mild, moderate, or severe AUD.

  • Study lasts 12 weeks with regular visits and assessments.
  • Participants must have HIV, be 18 or older, and meet alcohol use criteria.
  • Cannot participate if currently pregnant, receiving formal alcohol treatment, or have specific health conditions.
Study details
    Alcohol Use Disorder
    Hiv

NCT06004830

Yale University

3 May 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

  Other languages supported:

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.