Image

A Study to Learn About the Study Medicine (PF-06823859) in Adults With Active CLE or SLE With Skin Symptoms.

Examining PF-06823859 for skin symptoms in CLE or SLE patients.

Recruiting
18-75 years
All
Phase 2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is for adults with **cutaneous lupus erythematosus (CLE)** or **systemic lupus erythematosus (SLE)**, which are diseases causing skin problems. The study medicine, **PF-06823859**, is being tested to see if it is safe and effective. It will compare this medicine to a placebo, which looks like the real medicine but has no active drug. About 48 participants will join, with 32 getting the real medicine and 16 receiving the placebo. All treatments are given through an **intravenous infusion**, meaning it’s injected into the veins.

Participants will be in the study for around **65 weeks**. This includes time for choosing participants, receiving treatment, and having follow-up visits. The study will see if the medicine helps improve the **CLASI-A score**, a measure of skin symptoms.

Key Points:

  • The study lasts about 65 weeks, with regular visits and check-ups.
  • Participants must have CLE or SLE with specific skin symptoms to join.
  • Treatments are given by vein infusion, with some risks and requirements.
Print
Study details
    Lupus Erythematosus
    Systemic
    Lupus Erythematosus
    Cutaneous

NCT05879718

Pfizer

19 April 2025

Contact a study center
Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

  Other languages supported:

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.