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Department of Defense PTSD Adaptive Platform Trial - Master Protocol

Join our trial to explore new PTSD treatments.

Recruiting
18-65 years
All
Phase 2

Study Overview: This study is testing new treatments for PTSD (Post-Traumatic Stress Disorder), a condition where people feel stressed or scared even when they're not in danger, often after experiencing a traumatic event. The study is organized into three main parts: 30 days of screening to see if you qualify, 12 weeks of treatment, and 4 weeks of safety follow-up to ensure your well-being.

How It Works: The study is designed to test different medicines, with some people receiving a placebo (a harmless pill with no effect) to compare results. Participants won't know if they're receiving the actual medicine or the placebo, which is called double-blind testing. The study will adapt as it goes, adding new groups if necessary, and aims to find the best treatment options.

  • **Length of Study**: Approximately 4 months for each participant.
  • **Visits**: Regular check-ups will be required throughout the study.
  • **Eligibility**: Must be 18-64 years old, have PTSD symptoms, and be a current or former military member.

Note: Participants should not be pregnant, have certain mental health conditions, or be taking specific medications. If you're interested, you may need to undergo tests, like blood draws and MRIs.

Study details
    Post Traumatic Stress Disorder

NCT05422612

Global Coalition for Adaptive Research

17 May 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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