This study looks at how safe and effective the drug Tuvusertib is when used with other treatments for cancer. The study is open-label, meaning both doctors and patients know what treatment is given. Participants have advanced cancers that cannot be removed or treated with standard therapies. The research checks how the body responds to the drug and aims to find the best dose combination. The study has different parts focusing on various cancers like prostate, endometrial, and breast cancer. Some parts also compare how well the drug works in different forms, like tablets or capsules. This study involves regular check-ups and assessments to monitor safety and tumor response.

• Study involves multiple visits and check-ups.
• Participants get a new drug combination, which may help if standard treatments don’t work.
• There are potential risks, including side effects from the drugs.