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Perioperative Testosterone Replacement Therapy for the Improvement of Post-Operative Outcomes in Patients With Low Testosterone

Testing testosterone therapy to improve recovery after surgery for low testosterone.

Recruiting
18 years and older
Male
Phase 1

Testosterone Replacement Therapy is being studied to see if it helps patients with low levels of testosterone feel better after big surgeries, especially those involving the urinary system (urologic surgery). Testosterone is a hormone that helps build muscles and bones and may help patients recover faster after surgery. This study will check if giving extra testosterone is safe and if it helps people leave the hospital sooner and have fewer problems after surgery.

In this study, patients with low testosterone will get a shot of testosterone called testosterone cypionate into their muscles once a week for 3 months. There are two groups: one gets the testosterone shots, and the other receives regular care. The study will help decide if testing for testosterone and giving therapy should be part of surgery planning.

  • Study involves up to 3 months of treatment with weekly visits for shots.
  • Participants must be scheduled for a major surgery with an overnight hospital stay.
  • Not suitable for those with certain medical histories, like previous hormone treatments.
Study details
    Hypogonadism
    Malignant Urinary System Neoplasm
    Urinary System Disorder
    Urinary System Neoplasm

NCT04731376

Emory University

30 March 2025

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