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A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder

Comparing TAR-200 and cetrelimab with standard therapy for bladder cancer.

Recruiting
18 years and older
All
Phase 3

This study is for people with muscle-invasive bladder cancer (MIBC), which means the cancer has spread into the muscle of the bladder. It compares two treatments: a new method using a device called TAR-200 with a drug called cetrelimab against the usual treatment of chemoradiotherapy (using chemicals and radiation to kill cancer cells). The goal is to see which treatment helps people live longer without needing bladder removal surgery.

  • This study is only for those who can't or choose not to have bladder removal surgery.
  • Participants must pass certain health tests and have no other major cancer or severe bladder damage.
  • It includes regular health checks and treatment monitoring.

Before joining, discuss with your doctor if you meet the health criteria, and understand the potential risks and benefits of participating. You'll receive treatments and will be monitored to compare how well each treatment works in keeping the bladder cancer-free.

Study details
    Urinary Bladder Neoplasms

NCT04658862

Janssen Research & Development, LLC

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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