**Crohn's disease** is a condition that causes the intestines to become red and swollen. This can lead to stomach pain, diarrhea, and trouble growing in kids. Doctors think it might be related to bacteria, diet, or family history. Treatment often includes **anti-TNF therapy**, which involves medicines given through shots or IV to reduce swelling. This study, called the **CAMEO study**, looks at how well kids with Crohn's heal after starting this treatment. Doctors will check the healing by looking at the inside of the intestines using tests like a **colonoscopy** and a special MRI. Kids aged 6-17 who are newly diagnosed with Crohn's and start anti-TNF treatment within 6 months can join. The study aims to understand why some kids heal better than others so doctors can provide better care.

• Study lasts up to 5 years with visits before, during, and after one year of treatment.
• Participants need to complete various tests, like blood and stool samples, and MRIs.
• No extra risks beyond typical Crohn's disease treatment.