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Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

Studying cholesterol-lowering medication effects in older adults.

Recruiting
75 years and older
All
Phase 4

PREVENTABLE Study is a research project to see if a medicine called atorvastatin can help people aged 75 and older who don't have heart disease or memory problems stay healthy. Atorvastatin is a type of drug called a statin, used to lower cholesterol. The study compares atorvastatin to a placebo, which is a pill that looks like the real medicine but doesn't have any active ingredients. This study will last up to 5 years. Participants will be randomly assigned to take either atorvastatin or a placebo and will be regularly checked by phone calls to see how they're doing. If you join, the study will send you the medicine every 90 days. It involves community engagement and uses technology like phone and telehealth for easy participation.

  • Study lasts up to 5 years, with phone check-ins.
  • Participants get free study medicine every 90 days.
  • Open to adults 75+ without heart disease or dementia.
Study details
    Cognitive Impairment
    Mild
    Dementia
    Cardiovascular Diseases

NCT04262206

Duke University

28 June 2025

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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