This study is testing a medicine called VBI-S to see if it can help raise blood pressure in people with septic shock. Septic shock happens when a bad infection causes your blood pressure to drop dangerously low. This can be very serious because it might harm your organs. Hypovolemia means having less blood or fluids in the body than needed. In this study, some patients will get VBI-S and others might get different treatments to see which works better. The study is randomized, meaning patients are randomly chosen for each treatment group so doctors can compare the results fairly.

• Participants must be at least 18 years old and have specific signs of sepsis.
• People can't join if they have certain health problems, like heart issues or are pregnant.
• A special Data Safety Monitoring Board will check the study's safety throughout.