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A Study Evaluating the Efficacy and Safety of Vixarelimab in Participants With Idiopathic Pulmonary Fibrosis and in Participants With Systemic Sclerosis-Associated Interstitial Lung Disease

Exploring Vixarelimab's effects on lung diseases in a clinical study.

Recruiting
18-85 years
All
Phase 2

This study is testing a medicine called vixarelimab to see if it helps people with lung diseases like Idiopathic Pulmonary Fibrosis (IPF) and Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD). IPF makes lungs stiff and hard to breathe, while SSc-ILD involves thickening and scarring in the lungs. The study compares vixarelimab to a placebo (a "fake" treatment) to see if it improves lung function.

Participants take part for 52 weeks and can choose to continue for another 52 weeks with the real medicine. The study is split into two groups: one for people with IPF and the other for those with SSc-ILD. It is important to know that the first group is full, but the second group is still accepting participants.

  • The study lasts for 1 to 2 years, depending on participation in the optional extension period.
  • Participants may receive treatment with vixarelimab for the second year.
  • Potential risks include respiratory infections and other side effects related to lung diseases.
Study details
    Idiopathic Pulmonary Fibrosis
    Systemic Sclerosis With Lung Involvement

NCT05785624

Genentech, Inc.

17 May 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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