This study looks at how safe and effective the **Symplicity Spyral** system is for people with high blood pressure that isn't controlled well. High blood pressure, also called hypertension (HTN), is when the force of your blood against your artery walls is too high. The study focuses on a treatment called renal denervation (RDN), which uses a special tool to help lower blood pressure by working on the nerves near your kidneys. The study also involves checking in on people who were part of earlier studies called SPYRAL HTN-OFF MED and SPYRAL HTN-ON MED.

Key Points to Consider:

• The study is single-arm, which means all participants receive the same treatment.
• Participants should have a systolic blood pressure of 140 mmHg or higher.
• Some people cannot join, like those with kidney issues or women who are pregnant.