This study tests a new medicine called Pegozafermin to see if it helps people with very high levels of fats in their blood, known as severe hypertriglyceridemia. This means your triglyceride levels, which are a type of fat in the blood, are between 500 and 2000 mg/dL. The study lasts 26 weeks, which is about six months.

Key Points:

• Duration: The study is 26 weeks long.
• Participation Requirements: You must be at least 22 years old and keep your diet, medication, and exercise stable during the study.
• Exclusions: You cannot participate if you have certain illnesses like hepatitis, HIV, uncontrolled diabetes, or recent pancreatitis.

Before joining, ensure your current treatments for heart-related issues are stable. You should not have certain health conditions like Type 1 diabetes or gallstone diseases. If you want to participate, it's important to be ready to stick to your regular health routine and attend study visits. Discuss with your doctor to see if this study is right for you.