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A Study of XmAb20717 (Vudalimab)in Patients With Selected Advanced Gynecologic and Genitourinary Malignancies

Exploring XmAb20717 for advanced gynecologic and genitourinary cancers.

Recruiting
18 years and older
All
Phase 2

This study is testing a drug called **vudalimab (XmAb20717)** in people with certain advanced cancers, specifically in the **gynecologic** (female reproductive system) and **genitourinary** (urinary system and male reproductive organs) areas. The study has two stages: In **Stage 1**, different groups of 10 people each with specific cancer types will try the drug to see if it helps. If at least 2 people in a group show improvement, more people will join in **Stage 2** to see if the drug continues to work well.

Participants must be adults (18+), have tried standard treatments that didn’t work, and meet specific cancer criteria. Women must use effective birth control, and men shouldn’t donate sperm during the study. You can’t join if you’re on other cancer treatments or have certain health issues.

  • Study Length: The study may have multiple visits over time.
  • Risks: Possible side effects from the drug, not specified in detail.
  • Compensation: Not mentioned, check with the study team for details.
Study details
    Ovarian Cancer
    Clear Cell Carcinoma
    Endometrial Cancer
    Cervical Carcinoma
    Metastatic Castration-Resistant Prostate Cancer (mCRPC)

NCT05032040

Xencor, Inc.

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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