This study is testing a new eye medicine called **NCX 470**. It will compare NCX 470 to another medicine called **latanoprost**. Both are used for people with **open-angle glaucoma** (a common eye condition where fluid pressure builds up) or **ocular hypertension** (high pressure inside the eye without damage). **Intraocular pressure (IOP)** is the pressure inside the eye. Keeping this pressure low helps prevent vision loss. Participants will use one of the two treatments every evening for up to 12 months. Doctors will check if the medicine works and is safe.

Key Points:

• Duration: The study lasts up to 12 months.
• Visits: You will need to visit the doctor several times.
• Treatment: You will use eye drops once a day.

To join, you need to have open-angle glaucoma or ocular hypertension. You should not have had certain eye surgeries recently or have severe eye issues. Always talk to your doctor to learn more and see if this study is right for you.