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A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors

Trial for LY4101174 in advanced or recurring solid tumors.

Recruiting
18 years and older
All
Phase 1

This study is testing a new drug, LY4101174, to see if it is safe and works well for people with serious solid tumors, which are cancerous lumps in the body. The study has two parts: Phase 1a checks safety and finds the best dose, while Phase 1b sees how well the drug works at this dose. The study could last up to 4 years. It involves people with specific types of cancer, like breast or lung cancer, and requires a certain health status, called ECOG performance status, which rates how well you can do daily activities. Participants cannot join if they have certain health problems, such as uncontrolled diabetes or recent serious heart issues.

  • Study length is about 4 years with different phases.
  • Participants must have specific types of cancer and meet health criteria.
  • Excludes those with certain medical conditions or recent treatments.
Study details
    Metastatic Solid Tumor
    Recurrent Solid Tumor
    Advanced Solid Tumor
    Urinary Bladder Neoplasm
    Triple Negative Breast Cancer
    Non-small Cell Lung Cancer
    Esophageal Cancer
    Pancreatic Cancer
    Ovarian Cancer
    Cervical Cancer
    Head and Neck Squamous Cell Carcinoma
    Prostate Cancer
    Renal Pelvis Cancer
    Bladder Cancer

NCT06238479

Eli Lilly and Company

2 February 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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