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A Study of Tirzepatide (LY3298176) Once Weekly in Adolescent Participants Who Have Obesity or Overweight With Weight-Related Comorbidities

Testing tirzepatide for teens with obesity or weight-related health issues.

Recruiting
12-17 years
All
Phase 3

This study is testing a medicine called tirzepatide in kids and teens who are overweight or have obesity. Obesity means having a Body Mass Index (BMI) at or above the 95th percentile for one's age and sex, while overweight is a BMI between the 85th and 95th percentiles. BMI is a way to measure body fat using height and weight. Participants must also have a health problem linked to their weight, like high blood pressure, high cholesterol, or sleep issues.

The study lasts about 90 weeks, which is almost two years, and there could be up to 25 visits to the doctor. Participants with Type 2 Diabetes can join if they have been managing it with diet, exercise, or a stable medication called metformin.

Some people can't join, like those who have lost a lot of weight recently, have Type 1 Diabetes, or have a family history of certain cancers. They're also not allowed to take weight-loss meds or plan weight-loss surgeries during the study.

  • The study lasts around 90 weeks with up to 25 doctor visits.
  • Participants may have a weight-related health problem.
  • Some conditions and recent weight changes can disqualify you.
Study details
    Obesity
    Overweight

NCT06075667

Eli Lilly and Company

1 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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